Digestive System– The digestive system is also being negatively affected by the increased production of mucus, the main impact being the lack of the ability of the pancreatic enzymes that break down things like fats, and proteins to be released because the pancreas is coated with the aforementioned thick and sticky mucus. Which leads to malabsorption, and in turn malnutrition. This creates an environment where gaining weight is a serious problem, to combat that CF patients need to increase the amount of calories they intake, which again are not able to be well digested…leading to, digestive problems, gastrointestinal issues, frequent diarrhea, and gas. The only way to combat this is to take pancreatic enzymes in the form of a pill. These pills need to be taken whenever anything with any real nutritional value is eaten, exceptions being things like fruit, or liquids. But, even certain liquids (milk for example) require the ingestion of enzymes, otherwise there are consequences in the form of diarrhea. To add on to the litany of problems in that “direction”, there is in the other direction acid reflux, caused by gastrointestinal reflux disease, or GERD. Which, in and of itself brings an entirely new set of problems.